FIH-1/c-Kit Signaling: A Novel Contributor to Corneal Epithelial Glycogen Metabolism
نویسندگان
چکیده
منابع مشابه
Novel materials to enhance corneal epithelial cell migration on keratoprosthesis.
PURPOSE To introduce a new modification for silicone optical core Keratoprosthesis. METHODS Using mixtures of 2-hydroxyethyl methacrylate and acrylic acid polydimethylsiloxane (PDMS) films were modified with two-step oxygen plasma treatment, and then type I collagen was immobilised onto this modified surfaces. Both the biocompatibility of the modified films and cell behaviour on the surface o...
متن کاملDefective Wnt Signaling: A Potential Contributor to Cardiometabolic Disease?
Hypertension is a major public health problem associated with the increased risk for heart disease and stroke, leading causes of death worldwide. Despite recent treatment advances, hypertension remains present in approximately one-third of adults in the U.S. (1). The majority of hypertensive subjects are now obese and many suffer from insulin resistance, which exacerbates the risk for cardiovas...
متن کاملEffects of ultraviolet radiation on corneal epithelial metabolism.
Acute exposure to ultraviolet light to 257 nm wavelength produced a photokeratitis associated with characteristic metabolic alterations of corneal epithelial metabolism in rabbits. Significant increases in corneal hydration occurred simultaneously with decreased corneal epithelial glycogen content, but adenosine triphosphate content and enzyme activity of epithelial extracts were not affected d...
متن کاملCarboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing.
PURPOSE In this study, the ability of carboxymethylcellulose (CMC), used in artificial tear formulations, to interact with corneal-epithelial-cells (HCECs) and facilitate corneal epithelial wound healing was investigated. METHODS HCECs were incubated with fluorescein-labeled CMC (F-CMC). CMC-epithelial binding was measured by spectrophotometry. The effect on F-CMC binding by hyaluronic acid (...
متن کاملUV-induced signaling pathways associated with corneal epithelial cell apoptosis.
PURPOSE UV-C irradiation of corneal epithelial cells elicits K+ channel activation, which in turn causes them to undergo apoptosis. In the present study, the intermediary role played by mitogen-activated protein kinase (MAPK) signaling pathways in mediating this response was investigated. METHODS Western blot and kinase assays were used to measure UV-induced activation (i.e., phosphorylation)...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2013
ISSN: 1552-5783
DOI: 10.1167/iovs.12-11512